Past publications specific to Childhood Developmental Disorders (CDD) by Thoughtful House Director of Research, Dr. Andrew J. Wakefield:
CDD and Gastrointestinal Disease
- Wakefield AJ, Anthony A, Murch SH, Thomson M, Montgomery SM, Davies S, Walker-Smith JA. Enterocolitis in children with developmental disorder. American Journal of Gastroenterology 2000;95:2285-2295 Read more
- Furlano RI, Anthony A, Day R, Brown A, McGavery L, Thomson MA, Davies SE, Berelowitz M, Forbes A, Wakefield AJ, Walker-Smith JA, Murch SH. Colonic CD8 and gamma delta T-cell infiltration with epithelial damage in children with autism. Journal of Pediatrics 2001;138:366-72.
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- Wakefield AJ. The New Autism (Invited Article) Clinical Child Psychology & Psychiatry 2002;7:518-528
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- Wakefield AJ., Puleston J. Montgomery SM., Anthony A., O’Leary J.J., Murch SH Entero-colonic encephalopathy, autism and opioid receptor ligands. Alimentary Pharmacology & Therapeutics. 2002;16:663-674
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- Torrente F., Machado N., Perez-Machado M., Furlano R., Thomson M., Davies S., Wakefield AJ, Walker-Smith JA, Murch SH. Enteropathy with T cell infiltration and epithelial IgG deposition in autism. Molecular Psychiatry. 2002;7:375-382
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- Wakefield AJ, Ashwood P, Limb K, Anthony A. The significance of ileo-colonic lymphoid nodular hyperplasia in children with autistic spectrum disorder. European Journal of Gastroenterology and Hepatology 2005: 17
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- Ashwood P, Anthony A, Pellicer AA, Torrente F, Wakefield AJ. Intestinal lymphocyte populations in children with regressive autism: Evidence for extensive mucosal immunopathology. Journal of Clinical Immunology, 2003;23:504-517.
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- Ashwood P, Anthony A, Torrente F, Wakefield AJ., Spontaneous mucosal lymphocyte cytokine profiles in children with regressive autism and gastrointestinal symptoms: Mucosal immune activation and reduced counter regulatory interleukin-10. Journal of Clinical Immunology. 2004:24:664-673
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- The Gut-Brain Axis in Childhood Developmental Disorders: Viruses and Vaccines. Wakefield AJ., Collins I., Ashwood P. Invited chapter in Infectious Disease and Neuropsychiatric Disorders Chapter 21, pp 198-206. Ed. S.H. Fatemi
- Wakefield AJ. The Gut-Brain Axis in Childhood developmental Disorders. Journal of Pediatric Gastroenterology and Nutrition. 2002;34:S14-S17
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- Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, Berelowitz M, Dhillon AP, Thomson MA, Harvey P, Valentine A, Davies SE, Walker-Smith JA: Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet 1998 Feb 28;351(9103): 637-41
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- Ashwood P, Wakefield A. Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms. Journal of Neuroimmunology: 2006 Feb 20.
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- Wakefield A, Stott C, Limb K. Gastrointestinal comorbidity, autistic regression and Measles-containing vaccines: positive re-challenge and biological gradient. Medical Veritas: 3 (2006) 796–802.
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Etiology of CDD
- Wakefield AJ and Montgomery SM. Autism, viral infection and measles mumps rubella vaccination. Israeli Medical Association Journal 1999;1:183-187
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- Montgomery SM, Morris DL, Pounder RE, Wakefield AJ. Paramyxovirus infections in childhood and subsequent inflammatory bowel disease. Gastroenterology 1999;116:796-803
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- Kawashima H., Takayuki M., Kashiwagi Y., Takekuma K., Hoshika A., Wakefield AJ. Detection and sequencing of measles virus from peripheral blood mononuclear cells from patients with inflammatory bowel disease and autism. Digestive Diseases and Sciences. 2000;45:723-729
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- Wakefield AJ and Montgomery SM. Measles, mumps, rubella vaccine: through a glass, darkly. Adverse Drug Reactions & Toxicological Reviews 2000;19:265-283
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- Uhlmann V., Martin C, Shiels, Wakefield AJ, O.Leary JJ. Possible viral pathogenesis of a novel paediatric inflammatory bowel disease. Molecular Pathology 2002;55:84-90
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- Bradstreet JJ., El Dahr J., Anthony A., Kartzinel J., Wakefield AJ, Detection of Measles Virus Genomic RNA in Cerebrospinal Fluid of Children with Regressive Autism: a Report of Three Cases Journal of American Physicians and Surgeons. 2004.9:39-45
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- Wakefield AJ. Enterocolitis, autism and measles virus. Molecular Psychiatry. 2002;7:S44-46
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- O'Leary JJ, Uhlmann V, Wakefield AJ. Measles virus and autism. Lancet. 2000;356:772 (letter)
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- Wakefield AJ. MMR vaccination and autism. Lancet. 1999;354:949-50 (letter)
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- Stott C., Blaxill M., Wakefield AJ. MMR and Autism in Perspective: the Denmark Story. Journal of American Physicians and Surgeons 2004;9:89-91
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- Wakefield AJ. Entero-colitis, Autism and Measles Virus. Consensus in Child Neurology. 2002;6:74-77
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Publications by Dr. Carol Stott:
- Stott CM, Burden V, Forge J, Goodyer, IM. The Cambridge Language and Speech Project. Preliminary Findings on Language and Behaviour. (Chapter 7 in Communication and the Mentally Ill Patient (France, J. and Muir, N. Eds.) Jessica Kingsley Publishers, London: 1996.
- Baron-Cohen S, Wheelwright S, Stott CM, Bolton PF, Goodyer IM. Is there a link between engineering and autism. Autism 1, 1996:153-163.
- Baron-Cohen S, Wheelwright S, Stott CM, Bolton PF, Goodyer IM. Engineering and Autism: Exploring the link further: Reply to Wolff, Brausberg and Islam. Autism 2. 1996:92 –104.
- Burden V, Stott CM, Forge J, Goodyer IM. The Cambridge Language and Speech Project. (i) Detection of Language Difficulties at 36-39 months' Developmental Medicine and Child Neurology 38, 1996:613-631.
- Bolton PF, Merricks MJ, Stott CM, Goodyer IM. Language Impairment: Patterns of familial aggregation. American Journal of Medical Genetics. 1997:4, 656-657.
- Merricks MJ, Stott CM, Goodyer IM, Bolton PF. Obstetric Complications in Specific Language Impairment. American Journal of Medical Genetics. 1997:74:570.
- Jaffa A, Stott CM. Do inpatients on Adolescent Units Recover? A study of outcome and acceptability of treatment. European Journal of Child and Adolescent Psychiatry 1999:8,(4) 292-300.
- Williams DF, Ishikawa-Brush Y, Cleak JD, Fisher SE, Marlow AJ. Baird G, Jannoun L, Stott CM, Bolton PF, Goodyer IM, Bishop DVM, Monaco AP. A genome wide screen for loci involved in Specific Language Impairment (SLI). European Journal of Human Genetics. 2000:8 (1) 47.
- Williams D, Stott CM, Goodyer IM, Sahakian BJ. Specific Language Impairment with or without Hyperactivity: Neuropsychological evidence for fronto-striatal dysfunction. Developmental Medicine and Child Neurology. 2000:42 (6) 368-375.
- Stott CM, Merricks MJ, Bolton PF, Goodyer IM. Screening for Speech and Language Disorders: the reliability, validity and accuracy of the General Language Screen. International Journal of Language and Communication Disorders. 2001:32:2 133-151.
- Newbury DF, Bonora E, Fisher SE, Lai1 CSL, Baird G, Jannoun L, Slonims V, Stott CM, Bolton PF, Bailey A, Monaco AP, and the International Molecular Genetics of Autism Consortium (IMGSAC). FOXP2 is not a major susceptibility gene for autism or Specific Language Impairment (SLI). American Journal of Human Genetics. 2002:70 (5) 1318 – 1327.
- The Specific Language Impairment Consortium (SLIC) Universities of Oxford, Cambridge, Manchester and Aberdeen, Guys Hospital, London UK. Monaco A, Bolton P, Stott CM, and associated authors. A Genome-Wide Scan Identifies Two Novel Loci Involved in Specific Language Impairment (SLI). American Journal of Human Genetics. 2002:70 (2), 384-398.
- Merricks MJ, Stott CM, Goodyer IM, Bolton PF. The Aetiology of Specific Language Impairment: No Evidence of a Role for obstetric complications. The Journal of Neural Transmission. 2004:111 (7) 773-89.
- The Specific Language Impairment Consortium (SLIC) Universities of Oxford, Cambridge, Manchester and Aberdeen, Guys Hospital, London UK. Monaco, A., Bolton, P, Stott CM and associated authors. Highly significant linkage to SLI locus in an expanded sample of individuals affected by Specific Language Impairment (SLI). American Journal of Human Genetics: 2004:74 (6) 1225-1238.
- Stott CM, Blaxill M, Wakefield AJ. Commentary: MMR and Autism in Perspective: The Denmark Story. Journal of American Physicians and Surgeons. 2004:9 (3)89-91.
- Williams J, Scott F, Stott C, Allison C, Bolton P, Baron-Cohen S, Brayne C. The CAST (Childhood Asperger Syndrome Test): Test Accuracy. Autism. 2005 9:45-68.
- Compston JE, McConachie C, Stott C, Hannon RA, Kaptoge S, Debriam I, Love S, Jaffa A. Changes in bone mineral density, body composition and biochemical markers of bone turnover during weight gain in adolescents with severe anorexia nervosa: a 1-year prospective study. Osteoporos Int.. 2006 Jan;17(1):77-84.
- Wakefield AJ, Stott CM, Limb K. Gastrointestinal Comorbidity in Children with Autistic Spectrum Disorder and Re-Exposure to Measles-Containing Vaccines. Medical Veritas. 2006(3)796-802.
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